Open Access Research Article

Reliable Prediction of Insulin Resistance by a School-Based Fitness Test in Middle-School Children

Todd Varness1*, AaronL Carrel1, JensC Eickhoff2 and DavidB Allen1

Author Affiliations

1 Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4/4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792-4108, USA

2 Department of Statistics, Colorado State University, 206 Statistics Building, Fort Collins, CO 80523, USA

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International Journal of Pediatric Endocrinology 2009, 2009:487804 doi:10.1155/2009/487804

Published: 17 September 2009

Abstract

Objectives. (1) Determine the predictive value of a school-based test of cardiovascular fitness (CVF) for insulin resistance (IR); (2) compare a "school-based" prediction of IR to a "laboratory-based" prediction, using various measures of fitness and body composition. Methods. Middle school children () performed the Progressive Aerobic Cardiovascular Endurance Run (PACER), a school-based CVF test, and underwent evaluation of maximal oxygen consumption treadmill testing ( max), body composition (percent body fat and BMI z score), and IR (derived homeostasis model assessment index []). Results. PACER showed a strong correlation with max/kg ( = 0.83, ) and with ( = , ). Multivariate regression analysis revealed that a school-based model (using PACER and BMI z score) predicted IR similar to a laboratory-based model (using max/kg of lean body mass and percent body fat). Conclusions. The PACER is a valid school-based test of CVF, is predictive of IR, and has a similar relationship to IR when compared to complex laboratory-based testing. Simple school-based measures of childhood fitness (PACER) and fatness (BMI z score) could be used to identify childhood risk for IR and evaluate interventions.