Email updates

Keep up to date with the latest news and content from International Journal of Pediatric Endocrinology and BioMed Central.

Open Access Research Article

Reliable Prediction of Insulin Resistance by a School-Based Fitness Test in Middle-School Children

Todd Varness1*, AaronL Carrel1, JensC Eickhoff2 and DavidB Allen1

Author Affiliations

1 Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4/4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792-4108, USA

2 Department of Statistics, Colorado State University, 206 Statistics Building, Fort Collins, CO 80523, USA

For all author emails, please log on.

International Journal of Pediatric Endocrinology 2009, 2009:487804  doi:10.1155/2009/487804

Published: 17 September 2009

Abstract

Objectives. (1) Determine the predictive value of a school-based test of cardiovascular fitness (CVF) for insulin resistance (IR); (2) compare a "school-based" prediction of IR to a "laboratory-based" prediction, using various measures of fitness and body composition. Methods. Middle school children () performed the Progressive Aerobic Cardiovascular Endurance Run (PACER), a school-based CVF test, and underwent evaluation of maximal oxygen consumption treadmill testing ( max), body composition (percent body fat and BMI z score), and IR (derived homeostasis model assessment index []). Results. PACER showed a strong correlation with max/kg ( = 0.83, ) and with ( = , ). Multivariate regression analysis revealed that a school-based model (using PACER and BMI z score) predicted IR similar to a laboratory-based model (using max/kg of lean body mass and percent body fat). Conclusions. The PACER is a valid school-based test of CVF, is predictive of IR, and has a similar relationship to IR when compared to complex laboratory-based testing. Simple school-based measures of childhood fitness (PACER) and fatness (BMI z score) could be used to identify childhood risk for IR and evaluate interventions.