Research Article
Reliable Prediction of Insulin Resistance by a School-Based Fitness Test in Middle-School Children
1 Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4/4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792-4108, USA
2 Department of Statistics, Colorado State University, 206 Statistics Building, Fort Collins, CO 80523, USA
International Journal of Pediatric Endocrinology 2009, 2009:487804 doi:10.1155/2009/487804
Published: 17 September 2009Abstract
Objectives. (1) Determine the predictive value of a school-based test of cardiovascular fitness
(CVF) for insulin resistance (IR); (2) compare a "school-based" prediction of IR to
a "laboratory-based" prediction, using various measures of fitness and body composition.
Methods. Middle school children (
) performed the Progressive Aerobic Cardiovascular Endurance Run (PACER), a school-based
CVF test, and underwent evaluation of maximal oxygen consumption treadmill testing
(
max), body composition (percent body fat and BMI z score), and IR (derived homeostasis model assessment index [
]). Results. PACER showed a strong correlation with
max/kg (
= 0.83,
) and with
(
=
,
). Multivariate regression analysis revealed that a school-based model (using PACER
and BMI z score) predicted IR similar to a laboratory-based model (using
max/kg of lean body mass and percent body fat). Conclusions. The PACER is a valid school-based test of CVF, is predictive of IR, and has a similar
relationship to IR when compared to complex laboratory-based testing. Simple school-based
measures of childhood fitness (PACER) and fatness (BMI z score) could be used to identify childhood risk for IR and evaluate interventions.



